CVS! Walgreens! Rite Aid!
most major drugstores have Loyalty Card programs - those plastic hangtag thingies on your keychain? free to join, but handy for discounts!
each store has different programs, and different quirks. personally, i find trying to get all the deals at all the stores to be too much of a hassle. so i suggest you pick one to use most often.
i'm a big fan of CVS - there's a huge, clean, well-lit, 24-hour location not far from our house and i freely admit i enjoy going there!
but whichever drugstore you choose.... it isn't just for prescriptions and getting pictures developed! truly! some of the most amazing bargains you can find when couponing, will be found at the drugstore!
CVS has their ExtraCare card, and their ExtraCare Beauty Club. both free to join, but with fantastic benefits!
and when you first join the ExtraCare Beauty Club, a 10% off beauty items coupon will print out on your receipt! it expires after 3 days, and doesn't include sale items, but it's a nice welcome bonus!
i know i told you before that i'd only ever tell you to pay for two things, but if you can add the purchase of a 99¢ Green Bag Tag to your first CVS purchase, it will pay for itself. See, they're encouraging their customers to use reusable shopping bags, so if you have your Green Bag Tag scanned with each purchase where your bring your own bag (or buy something that doesn't need a bag, like detergent), with every fourth scan, you'll get a $1 ExtraBuck printed on your receipt. (you can only get credit for one scan per card, per store, per day)
straight off the top, CVS will give you 2% of your purchases back, quarterly, as ExtraBucks, $1 for every two prescriptions you have filled there, and the ExtraCare Beauty Club will give you $5 ExtraBucks for every $50 you spend on beauty items.
every week, different food and household items go on sale at CVS - and they're very coupon friendly! - i can almost promise you'll be amazed at some of the deals!